In addition, a “dental stem cell banking” is available for regenerative treatments in the future. The main features of stem cells in the future of. Stem cells can self-renew and produce different cell types, thus providing new strategies to regenerate missing tissues and treat diseases. In the field of dentistry. The mesenchymal stem cells (dental pulp stem cells; DPSC) found inside teeth represent a significant future source of stem cells for.


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Therapeutic potential of dental stem cells

The generated teeth had physical properties similar to that of normal human teeth except hardness about one-third less in hardness of human teeth. The reported advantages to such an dental stem cells were being noninvasive technique, low cost, and use of somatic cells instead of embryonic that are wasted anyways.

Interestingly urine-derived stem cells do not form tumors when transplanted in the body unlike other stem cells; more over autologous sourcing of these cells reduces the likelihood of rejection. The Obama administration has made stem cell research one of the pillars of his health program.

It is likely that the next stem cell advance is the availability of regenerative dental kits, which will enable the dentists the ability to deliver stem cell therapies locally as part of routine dental practice. An innovative method that holds promising future is to generate induced stem cells from harvested human dental stem cells stem cells.

This approach reprograms dental stem cells into an embryonic state, thus expanding their potential to differentiate into a much wider range of tissue types. dental stem cells

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Researchers have so far succeeded in making specific dental tissues or tooth like structures although in animal studies but future advances in dental stem cell research will be the regeneration of functional tooth in humans.

As human stem cell research is a relatively new area, companies developing cell therapies face several types of risks as well, and some are not able to manage them thus pushing this venture into a highly speculative enterprise. Present clinical trials are being performed on recombinant human fibroblast growth dental stem cells, human platelet-derived growth factor, and tricalcium phosphate GEM Looking at the ongoing clinical trials, it is too early to speculate whether all therapies based on stem cells will prove to be clinically effective.

dental stem cells

Stem Cells International

The oncogenic potential of these cells is still to be determined in long-term clinical studies. Dental stem cells, the research is mainly confined to animal models and their extensive clinical application is yet to be tested.

Other major limitations are the difficulty to identify, isolate, purify and grow these cells consistently in labs. Immune rejection is also one of the issues, which require a thorough consideration; nevertheless use of autologous cells can overcome this. Teeth-like structures cannot replace actual teeth, thus a considerable research research and development efforts is required to advance the dental regenerative therapeutics.

Researchers still need to grow blood and dental stem cells supply of teeth to make them fully functional. Although not currently available, these approaches may one day be used as biological alternatives to the synthetic materials currently used.

Like other powerful technologies, dental stem cell research poses challenges as well as risks. If we are to realize the benefits, meet the challenges, and avoid the risks, stem cell research must be conducted under effective, accountable systems of social-responsible oversight and control, at both the national and international levels.

Science, policy, and dental stem cells. One molecule of diphtheria toxin fragment a introduced into a cell can kill the cell. The Cell in Development and Inheritance. The lymphocyte as a stem cell, common to different blood dental stem cells in embryonic development and during the post-fetal life of mammals.


Mason C, Dunnill P. A brief definition of regenerative medicine.

Current overview on dental stem cells applications in regenerative dentistry

Restoration of lost regenerative capacity of dental tissues. Postnatal human dental pulp stem cells Dental stem cells in vitro and in vivo. Stem cells from human exfoliated deciduous teeth.

Mesenchymal stem cell-mediated functional tooth regeneration in swine.